Abstract:
This thesis describes the synthesis and characterization of Nickel(II), Cu(II), Zn(II) and
Cd(II) complexes of 4-n-octyloxybenzoylhydrazine in presence of various aldehydes.
The lignand precursor 4-n-octyloxybenzoylhydrazine 2 was prepared by the reaction of
ethyl-4-n-octyloxybenzoate,1 with excess hydrazine hydrate.
Ethyl-4-n-octyloxybenzoate was synthesized by the reaction of
ethyl-4-hydroxy-benzoate and 1-bromooctane in presence of anhydrous potassium
carbonate.
The reaction of ligand precursor 4-n-octyloxybenzoylhydrazine 2 with cinnamaldehyde,
4-methylbenzaldehyde, 4-nitrobenzaldehyde, 4-methoxybenzaldehyde,
4-chlorobenzaldehyde gave the ligands
CH3(CH 2)6CH 2O C
O
NHN=CHR
Where, R = C6H5CH=CH (3), p-CH3C6H4 (4), p-NO2C6H4(5), p-CH3OC6H4 (6),
p-ClC6H4 (7) respectively.
The reaction of ligands (3, 4, 5, 6, 7) with hydrated Ni(II) acetate gave the squareplaner
complexes of nickel(II)
[CH3(CH2)6CH2O C(O) NN=CHR]2Ni
Where R = C6H5CH=CH (8), p-CH3C6H4 (9), p-NO2C6H4(10), p-CH3OC6H4 (11),
p-ClC6H4 (12) respectively. The compounds were also prepared by template method.
The reaction of ligands (4, 5, 6, 7) with hydrated Cu(II) acetate gave the square-planer
complexes of copper(II).
[CH3(CH2)6CH2O C(O) NN=CHR]2Cu
Where R = p-CH3C6H4 (13), p-NO2C6H4(14), p-CH3OC6H4 (15), p-ClC6H4 (16)
respectively. The compounds were also prepared by template method.
Attempts were taken to occur the reactions of ligands (4, 5, 6, 7) with hydrated Zn(II)
acetate but only the ligand (7) gave the square-planer complex of zinc(II),
[CH3(CH2)6CH2O C(O) NN=CHR]2Zn
where, R= p-ClC6H4 (17) respectively. The compound was also prepared by template
method.
Attempts were also taken to occur the reactions of ligands (4, 5, 6, 7) with hydrated
Cd(II) acetate to give the complexes of cadmium(II) but no complex formed.
The obtained complexes were characterized by elemental analyses, magnetic moment,
conductance measurements, IR and 1H-NMR spectroscopic studies. Investigation of
biological activity of the synthesized compounds on pathogenic bacteria Escherichia coli
(gram –ve), Pseudomonas aeruginosa (gram –ve), Klebsiella spp (gram +ve), Bacillus
subtilis (gram +ve) Was undergone and appreciating activities was found.
Description:
This thesis is Submitted to the Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh for the Degree of Master of Philosophy (MPhil)
